研究業績

2022年

原著論文

• "Elucidation of late-stage biosynthesis of phomoidride: Proposal of cyclization mechanism affording characteristic 9-membered ring of fungal dimeric anhydride"
  Yamamoto, S.; Matsuyama, T.; Ozaki, T.*; Takino, J.; Sato, H.; Uchiyama, M.*; Minami, A.*; Oikawa, H.*
  J. Am. Chem. Soc. 144, 20998-21004 (2022).

  • DOI: 10.1021/jacs.2c09308

  異分野融合：内山先生（東京大学）、尾崎先生（東北大学）
• "Structure and biosynthesis of ribosomal lipopeptide antibiotic albopeptins"
  Oikawa, H.*; Mizunoue, Y.; Nakamura, T.; Fukushi, E.; Jiang, Y.; Ozaki, T.; Minami, A.; Isono, K.
  Biosci. Biotechnol. Biochem. 86, 717-723 (2022).

  • DOI: 10.1093/bbb/zbac039

  日本農芸化学会欧文誌論文賞受賞
• "Biosynthetic machineries of anthraquionones and bisanthraquinones in Talaromyces islandicus"
  Fukaya, M.; Ozaki, T.; Minami, A.*; Oikawa, H.*
  Biosci. Biotechnol. Biochem. 86, 435-443 (2022).

  • DOI: 10.1093/bbb/zbac009
• "Heterologous expression of a polyketide synthase ACRTS2 in Aspregillus oryzae produces host selective ACR-toxins: Co-production of minor metabolites"
  Kotani, A.; Ozaki, T.*; Takino, J.; Mochizuki, S.; Akimitsu, K.; Minami, A.*; Oikawa, H.*
  Biosci. Biotechnol. Biochem. 86, 287-293 (2022).

  • DOI: 10.1093/bbb/zbab214

  異分野融合：秋光先生（香川大学）
• "Mechanism of S-Adenosyl-L-methionine C-Methylation by Cobalamin-dependent Radical S-Adenosyl-L-methionine Methylase in 1-Amino-2-methylcyclopropanecarboxylic Acid Biosynthesis"
  *Kudo, F; Minato, A; Sato, S; Nagano, N; Maruyama, C; Hamano, Y. Hashimoto, J; Kozone, I; Shin-ya, K; *Eguchi, T
  Org. Lett. 24, 49, 8975-8979 (2022).

  • DOI: 10.1021/acs.orglett.2c03555
• "Structural Insight into the Reaction Mechanism of Ketosynthase Like Decarboxylase in a Loading Module of Modular Polyketide Synthases"
  Chisuga, T; Nagai, A; *Miyanaga, A; Goto, E; Kishikawa, K; Kudo, F; *Eguchi, T.
  ACS Chem. Biol. 17, 1, 198-206 (2022).

  • DOI: 10.1021/acschembio.1c00856

総説

• "Recent Advances in the Structural Analysis of Adenylation Domains in Natural Product Biosynthesis"
  *Miyanaga, A; Kudo, F; Eguchi, T
  Curr. Opin. Chem. Biol. 71, e102212, 2022 (2022).

  • DOI: 10.1016/j.cbpa.2022.102212
• "Biosynthesis of Cyclitols"
  *Kudo, F; *Eguchi, T
  Nat. Prod. Rep. 39, 1622-1642 (2022).

  • DOI: 10.1039/d2np00024e
• "Characterization of the Cobalamin-dependent Radical S-adenosyl-L-methionine Enzyme C-Methyltransferase Fom3 in Fosfomycin Biosynthesis"
  Sato, S; Kudo, F; *Eguchi, T
  Methods Enzymol. 669, 45_70 (2022).

  • DOI: 10.1016/bs.mie.2021.11.025

著書・解説

• "麹菌が切り拓く天然物化学～麹菌を利用した生物活性天然物の生産"
  南 篤志、尾_太郎、及川英秋
  発酵・醸造食品の最前線II（食品） (2022).