研究業績

2021年

原著論文

• "Biosynthetic studies of phomopsins unveil posttranslational installation of dehydroamino acids by UstYa family proteins"
  Sogahata, K.; Ozaki, T.*; Igarashi, Y.; Naganuma, Y.; Liu, C.; Minami, A.*; Oikawa, H.*
  Angew. Chem. Int. Ed. 60, 25729-25734 (2021).

  • DOI: 10.1002/anie.202111076
• "Biochemistry-guided prediction of absolute configuration of fungal reduced polyketide"
  Takino, J.; Kotani, A.; Ozaki, T.; Peng, W.; Yu, J.; Guo, Y.; Mochizuki, S.; Akimitsu, K.; Hashimoto, M.; Ye, T.*; Minami, A.*; Oikawa, H.*
  Angew. Chem. Int. Ed. 60, 23403-23411 (2021).

  • DOI: 10.1002/anie.202110658

  国際共同研究：叶先生（北京大学深セン大学院）
• "Genome-based discovery of enantiomeric pentacyclic sesterterpenes catalyzed by the fungal bifunctional terpene synthase"
  Jiang, L.; Zhang, X.; Sato, Y.; Zhu, G.; Minami, A.; Zhang, W.; Ozaki, T.; Zhu, B.; Wang, Z.; Wang, X.; Lv, K.; Zhang, J.; Wang, Y. -H.; Gao, S. -S.; Liu, C.; Hsiang, T.; Zhang, L.; Oikawa, H.*; Liu, X.*
  Org. Lett 23, 4645-4650 (2021).

  • DOI: 10.1021/acs.orglett.1c01361

  国際共同研究：劉先生（華東理工大学）
• "Biosynthesis of cyclochlorotine: Identification of the genes involved in oxidative transformations and intramolecular O,N-transacylation"
  Jiang, Y.; Ozaki, T.*; Liu, C.; Igarashi, Y.; Ye, Y.; Tang, S.; Ye, T.; Maruyama, J.; Minami, A.*; Oikawa, H.*
  Org. Lett. 23, 2616-2620 (2021).

  • DOI: 10.1021/acs.orglett.1c00525

  異分野融合：丸山先生（東京大学）
• "Biochemical and Mutational Analysis of Radical S-Adenosyl-L-Methionine Adenosylhopane Synthase HpnH from Zymomonas mobilis Reveals that the Conserved Residue Cysteine-106 Reduces a Radical Intermediate and Determines the Stereochemistry"
  Sato, S; *Kudo, F; Rohmer, M; *Eguchi, T
  Biochemistry 60, 38, 2865-2874 (2021).

  • DOI: 10.1021/acs.biochem.1c00536
• "Complex Structure of the Acyltransferase VinK and the Carrier Protein VinL with a Pantetheine Cross-linking Probe"
  *Miyanaga, A; Ouchi, R; Kudo, F; *Eguchi, T
  Acta Crystallographica Section F 77, 294-302 (2021).

  • DOI: 10.1107/S2053230X21008761
• "Mutational Biosynthesis of Hitachimycin Analogs Controlled by the β-Amino Acid-Selective Adenylation Enzyme HitB"
  *Kudo, F; Takahashi, S; Miyanaga, A; Nakazawa, Y; Nishino, K; Hayakawa, Y; Kawamura, K; Ishikawa, F; Tanabe, G; Iwai, N; Nagumo, Y; Usui, T; *Eguchi, T
  ACS Chem. Biol. 16, 3, 539_547 (2021).

  • DOI: 10.1021/acschembio.1c00003
• "Stepwise Post-glycosylation Modification of Sugar Moieties in Kanamycin Biosynthesis"
  *Kudo, F; Kitayama, Y; Miyanaga, A; Numakura, M; *Eguchi, T
  ChemBioChem 22, 9, 1668_1675 (2021).

  • DOI: 10.1002/cbic.202000839
• "One-pot Enzymatic Synthesis of 2-Deoxy-scyllo-inosose from D-Glucose and Polyphosphate"
  *Kudo, F; Mori, A; Koide, M; Yajima, R; Takeishi, R; Miyanaga, A; *Eguchi, T
  Biosci. Biotechnol. Biochem. 85, 1, 108_114 (2021).

  • DOI: 10.1093/bbb/zbaa025